2024-12-31T01:17:38-0500
In volunteers with hepatic cirrhosis Child Pugh A and B , sildenafil clearance was reduced, resulting in increases in AUC 85 and Cmax 47 compared to age matched volunteers with no hepatic impairment. Sildenafil did not affect the steady state pharmacokinetics of the HIV protease inhibitors, saquinavir and ritonavir, both of which are CYP3A4 substrates.
Judge rules in Diddy’s favor. Similar is between Bill Cosby‘s trial and Diddy trial.
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